Scientific Program

Conference Series Ltd invites all the participants across the globe to attend World Brain Congress Carlton Palace Hotel, Dubai. UAE.

Day 1 :

Conference Series BRAIN 2018 International Conference Keynote Speaker Khashayar Pazooki photo
Biography:

Khashayar Pazooki Group Psylux S.A / Neuroacademy Luxembourg Specialized In Neurobiology, Neurophysiology, Clinical Psychotherapy Sciences and Neurocognitive Sciences. Head of the Research Department at Group Psylux. S.A, Member Of The Scientific Committee Of Avm-Luxembourg, Head Of Traumainstitut Luxembourg and Neuro Academy Luxembourg, Lecturer At Different Institutes Such As Aap-Wien, Msk-Cario, Key Speaker At World Food Programme (Wfp) In Madrid, Guest Lecturer At Sigmund Freud Private University In Vienna.

 

Abstract:

Treatment success and positive outcomes are very important goals in clinical work. This research study shows significant positive changes in the treatment outcomes of a group of participants (n=9, average age:38-66 years). The application of this multimodal and innovative approach makes it possible to obtain very detailed differential diagnostic data and allow for the individualization and personalization of the therapeutic planning for the patients. This model provides an overview of dysfunctional correlations in respect of neurophysiological, neurobiological, peripheral and psychological functions that can be regulated with the Multi-Modal Treatment (MMT) approach in a more efficient and effective manner.

Conference Series BRAIN 2018 International Conference Keynote Speaker Justin James Kennedy photo
Biography:

Prof. Kennedy is a Thought Leader & Executive Coach in Organizational Neuroscience. His corporate career was interrupted by a motorbike accident, which left him in a coma. After several brain surgeries and a lengthy recovery process, he learned what was needed to reboot his brain again. With strict discipline and endless willpower, he presented a Ph.D. thesis based on his research in neuroscience in Switzerland several years later. He was invited to do a TED talk and presented his research in applied neuroscience at the Institute of Coaching, Harvard Medical School Conference, in Boston in 2016. His book "Brain Reboot - A Change of Mind Will Change Your Brain" will be published in 2018 and was endorsed by the #1 leading coach Dr. Marshall Goldsmith, in the USA.

Today Dr. Kennedy is a globally recognized professor of neuroscience and Organizational Behavior with bespoke Business Schools and Universities in Switzerland, the UK, South Africa, and the UAE. Besides his academic roles, Dr. Kennedy holds several US coaching accreditations and a clinical healthcare license. He runs an executive coaching practice (profkennedy.com) out of NY and Dubai and engages as keynote speaker in the US, Africa, and the Middle East, aspiring executives to peak performance.

He developed the neuroscience-based N3 Coaching model offering various programs designed to sustain well-being while developing behavioral techniques to perform at peak. His work is based on brain data to ensure medically measurable results in his clinical, academic and corporate work.

 

Abstract:

The literature has not yet been synthesized and there is a lack of clarity on what constitutes effective leadership for research use, in the Middle East or what kinds of intervention effectively develop leadership for the purpose of coaching and enhancing clinical practice. We synthesized the evidence on leadership coaching behaviors amongst nurses to then determine the effectiveness of interventions that promote these leadership behaviors Methods/Design A narrative synthesis will be further conducted to synthesize diverse forms of evidence. Narrative synthesis integrates evidence from multiple research designs, including experimental, quasi-experimental and observational studies to generate new insights for policy and practice and will be helpful in generating hypotheses for future experimental studies. This approach has been selected because the majority of leadership and management research is descriptive. A review of leadership research in health and business found that only 5 of 5,728 articles (less than 0.3%) investigated a correlation between leadership and measurable outcomes in nursing. With recent interests in healthcare leadership and research use, however, we anticipate more studies in the ME region. We used a systematic four-stage approach to conduct the review, in line with methodological guidelines set forth by Grimshaw. Using an integrated knowledge translation approach that supports a partnership between researchers and knowledge users throughout the research process, we further follow principles of knowledge synthesis using a systematic method to synthesize different types of evidence involving: searching the literature, study selection, data extraction, and quality assessment, and analysis. A narrative synthesis will be further conducted to explore relationships within and across studies and meta-analysis will be performed if sufficient homogeneity exists across studies employing experimental randomized control trial designs along with interviews of current nurses pre and post coaching. Findings and Discussion With coaching leadership to enhance engagement we will further synthesize healthcare and leadership research to understand what enables nurses to develop the leadership within an academy for the purpose of enhancing research use in clinical practice. The current results show a pressing need for such an academy. We present the medical, hospital needs achieved from the development of a leadership academy and coaching journey for nurses. The result has been the formulation of a leadership academy for nurses within a leading hospital group to coach and develops leading nurses.

  • Molecular Brain Research | Brain Diagnosis | Neuropsychiatry and Mental Health | Brain Degenerative Disorders | Case Reports in Neurological Medicine
Speaker

Chair

Khashayar Pazooki

Neuroacademy Luxembourg & Traumainstitut Luxembourg

Speaker

Co-Chair

Justin James Kennedy

Psychologist

Session Introduction

Jiri Novotny

Charles University, Czech Republic

Title: Alterations in the rat brain proteome induced by early maternal separation
Speaker
Biography:

Jiri Novotny is the Associate Professor of Animal Physiology, Charles University in Prague has completed his Ph.D. in 1996 at the Czech Academy of Sciences. He has worked as a Postdoctoral Associate in the Institute of Physiology, Czech Academy of Sciences and in 2007 he became a Head of the Department of Physiology, Faculty of Science, Charles University. His research has focused on the biochemistry of cell signaling under different physiological and pathophysiological conditions. He has published more than 80 papers in reputed journals and has been serving as an Editorial Board Member of several journals. 

Abstract:

Mother-infant contacts play an important role in the shaping of newborns' physiological system along with the development and maturation of the brain and behavior. There are some indications that stressful experiences in the early neonatal period may adversely affect the development of brain neurotransmitter systems and contribute to the development of certain mental illnesses. Here, we investigated the effect of early maternal separation on protein expression in selected brain regions and, in parallel we monitored the behavior of rat pups and young adults in a light-dark box. Rat pups (Long-Evans) were separated from their mothers on postnatal days 2 to 21 for 3h per day or normally reared. On day 22, some animals were subjected to the light-dark box test and the others were used for the isolation of brain tissue (cortex, hippocampus, and cerebellum). Some animals were maintained until 3 months of age and then used for analyses. Brain tissues were homogenized and subjected to label-free quantitative proteomic analysis. Results of proteomic analyses revealed differences in protein profiling of different brain regions and indicated that early maternal separation diversely affected protein expression in the cortex, hippocampus, and cerebellum. Changed protein expression was observed also in brain tissues from young adult rats. Animals subjected to maternal separation exhibited anxiety-like behavior, which lasted into young adulthood. In conclusion, these data demonstrate that early life stressful experiences may affect protein expression in some brain regions and lead to behavioral alterations.

Ammar Mallouhi

Medical University of Vienna, Austria

Title: Structural and microstructural 3T MR imaging of glioma
Speaker
Biography:

Ammar Mallouhi has completed his specialization in diagnostic radiology in Innsbruck, Austria in 2006 and he was awarded a Venia Docendi“ in 2007. Currently a consultant at the Department of Neuroradiology at Vienna Medical University in Vienna, Austria since 2010. In 2012, he was nominated as an associate professor at Vienna Medical University. He has published more than 50 papers and proceedings in reputed journals. He was awarded several international scientifi c awards including three “Certifi cate of Merit” from the RSNA.

Abstract:

MR imaging is an integral part of the management of gliomas. Morphologic and functional MR imaging modalities help in the assessment of location and extent of the tumor and of its biologic activity. techniques and imaging findings of WHO II, III and IV gliomas at structural (high-resolution T2W, Flair, MPR, SWI) as well as at functional (DWI and DTI, MR Spectroscopy, dynamic susceptibility-weighted contrast-enhanced MR perfusion, arterial spin labeling) MR imaging will be summarized. In particular, the predictive value of multimodality MRI in detecting anaplastic transformation and the Value of multimodality MRI in detecting pseudoprogression and pseudoresponse will be emphasized. The major teaching points of this presentation are: 
1. understanding the spectrum of key image characteristics of glioma at various 3T MR techniques. 2. conjoint interpretation of structural and functional MR imaging findings helps in recognizing glioma grade, tumor tendency for progression (upgrading) and tumor response after therapy. 3. choosing a multimodality MRI approach assists biopsy and surgery planning.
 

Speaker
Biography:

Kumaar Bagrodia is the Founder of NeuroLeap, India’s leading applied neuroscience company and also LeapVault group including digital healthcare.  Kumaar has several years of cross-functional expertise across industries and domains. He has earlier worked with companies like Infosys and WNS where he was an associate director globally. He has consistently been rated very highly by customers across the globe which include leading global investment banks, consulting firms, financial research houses and Fortune 100 corporates.  Kumaar holds an MBA degree from the University of Oxford, is a country champion and ambassador for the Oxford Business Alumni in India.  He has been featured in various media in India and abroad including [email protected], Wall Street Journal, The Economic Times, Hindustan Times, Bloomberg TV and Forbes to name a few. He co-authored an article in Harvard HBR.

Abstract:

Speaker
Biography:

Ahmad Tamimi Started his study at University of Oviedo graduating as Medical Doctor in 1977, he got his training in Neurosurgery at General Hospital of Asturias, Spain as from 1977-1981, he had his Ph.D. in Medicine from University of Oviedo, Spain, in 1981. He worked as a consultant at General Hospital of Asturias as from 1981until 1984, a consultant at General Hospital of Las Palmas as from 1984 until 1990, and consultant at Jordan University Hospital since 1990 till present. He was appointed as Chairman of Neurosurgical Department as from 2000 until 2013. In 2000, he became a full professor of Neurosurgery. Prof. Tamimi became a Dean of Medical School at Muatah University during the period from 2005-2007. and General Director of Jordan University Hospital from 2013-106. Member of the scientifi c committee the Arab Board in Neurosurgery and Member of the scientifi c committee Jordanian Board scientifi c committee member in Neurosurgery. Special interest in Neuro-oncology and epilepsy surgery. He is the author of over 150 publications in Neurosurgery, Medical Ethics, Medical Education and Health care system.

Abstract:

Background: Most epilepsy treatments are associated with low bone mineral density (BMD) and increased risk of bone fracture. Recent studies have demonstrated that cholinergic activity has an anabolic effect on bone metabolism. Vagus nerve stimulation (VNS) is a promising treatment of epilepsy that, as a side effect can increase cholinergic activity. Accordingly, we hypothesize that VNS can increase BMD in epilepsy patients. Methods: A series of 16 epilepsy patients (6 females and 10 males; 5 to 46 years old) scheduled for VNS insertion were assessed for BMD before and after the VNS insertion. VNS insertions were performed between May 2012 and October 2015. Paired t-test was used to compare BMD a before and a VNS. Results: Initial BMD z score values were - 1.1 ± 0.741 (mean ± SD) gr/cm2 for femoral neck and -1.027 ±1.129 for L1-L4. BMD has assessed 446.5 ±151.2 days ethics, VNS insertion. BMD from was significantly higher aft er VNS insertion for L1-L4 (p=0.033) with mean BMD increasing from -1.027 to – 0.897. VNS had no eff ect on the BMD of the femoral neck (p=0.62). Conclusions: Epilepsy patients undergoing VNS might benefi t from an improvement in lumbar spine BMD thereby decreasing the risk of bone fractures. Further studies are warranted to confi rm this finding.

Reza Nejat

Beheshti University of Medical Sciences (SBMU), Iran

Title: Neuroprotective effect of erythropoietin
Speaker
Biography:

Reza Nejat is a board certifi ed Anesthesiologist and FCCM. After graduating from Tehran University of Medical Sciences (TUMS) as a GP, he could achieve the ECFMG certifi cation and also board certifi cation in Anesthesiology from Iran University of Medical Sciences. He passed the fellowship programme in Critical Care Medicine at Sina Hospital, TUMS. During this period he was inclined to study molecular medicine in the fi eld of sepsis, acute heart failure, and neurocritical care. Administration of EPO to neurologically injured patients has been one of his fi eld of interests and experience for the past 4 years. He was the chief of few hospitals and associate professor in Shahid Beheshti University of Medical Sciences for 8 years. Dr. Nejat has 4 published books in the fields of cardiology, nephrology, fluid and electrolyte, nutrition, metabolism, and endocrinology. Recently, he contributed to the chapter of “Acute Heart Failure” in the reference book “Comprehensive Textbook of Therapeutics” studied by post-doc residents of pharmacotherapy. On his website, rezanejat.com, he publishes his articles. 
 

Abstract:

Statement of the Problem: During the last 25 years in an animal, ex-vivo, in-vitro and even in some clinical studies, cell protective effect of erythropoietin, a growth hormone used for erythropoiesis, was clarified even though the German Multicenter EPO Stroke Trial revealed that administration of this growth factor might even be hazardous to humans. On the contrary, a huge amount of studies thereafter, like the conclusion achieved in 2010 by Elmahdy and colleagues, could elucidate the anti-inflammatory cell-protective potentials of erythropoietin in neurological injuries and disorders recently categorized as, entities. The neuroprotective effect of this endo-hormone and its safety, if proved clinically might change the fate of many disabled patients in the future. Methodology & Theoretical Orientation: Near 270 articles including reviews and animal, in-vitro, ex-vivo and clinically case-control studies downloaded from science direct and PubMed websites were studied. Conclusion & Significance: It has long been believed that neural cells do not have the potentials to proliferate nor regenerate in case they encounter diverse sorts of insults including of hypoxic, hypoglycemic, oxidative and even apoptotic origin. A growing number of studies have shown that erythropoietin receptor is distributed extensively in the nervous system on the neurovascular unit cells and erythropoietin participates in many cell-protective anti-apoptotic pathways in the central and peripheral nervous systems. These pathways also have significant contributions to the plasticity of the neuronal tissues which by itself shows the probable role of this growth factor in even restoring of memory and intelligence in the post-injury period. A recent phase II study in infants with moderate to severe hypoxic/ischemic encephalopathy has demonstrated EPO’s effect in diminishing MRI brain injury and improving the motor function of the infant's after 1 year. It seems to be a must to conduct more sophisticated methodological case-control studies to elucidate the magical effects of this endo-hormone. 

Biography:

Chu Yin Man has obtained Master of Science degree in Stroke & Clinical Neurosciences in the Chinese University of Hong Kong. He is currently an Advanced Practice Nurse in an acute stroke unit and Visiting Lecturer in Institute of Advanced Nursing Studies in hospital authority. He had published studies on thrombolytic therapy, carotid doppler screening, TIA service and lifestyle interventions in stroke. He had also organized many health promotion programs for brain health and stroke prevention. His research interests are evidence-based practice, stroke physiology, patient education and lifestyle modifi cation for stroke management.
 

Abstract:

Over 15 million people have suffered from a stroke every year. Studies showed that approximate one-third acute stroke patient would deteriorate after admission. In the acute phase of cerebral ischemia, the affected area is composed of an infarct core which is surrounded by penumbra area. The cerebral blood flow will diminish further and the brain cells cannot survive. The preservation of cerebral blood flow or cerebral perfusion is essential. Stroke is frightening to patient and family members, as it causes serious disability. Often people believe that active training can promote recovery. In fact, undue activities will diminish cerebral blood flow to the affected brain tissue and cause irreversible damage. Health care professional has the duty to correct patient and family's misconceptions at this time. It is crucial that the patient can understand the rationales and comply with management. A systematic review has been conducted to understand the patients’ and families’ information needs during admission of stroke and examine various methods in patients’ and families’ education in stroke. This systematic review concluded the information needs of stroke patients and carers persist from the admission period until the discharge process and further caring in the community. However, the information needs on acute stroke admission are not well researched, especially its therapeutic interplay towards patients and carers. Although education strategies such as personalized written materials have been developed for better patients and carers understanding and treatment compliance, the coverage of different types of stroke patients is limited and the outcome is limited.