6^th World Brain Congress

The emerging RNA-centric world of neurobiology refers to the growing recognition of the pivotal role that RNA molecules play in the complex functions of the nervous system.

Here are some key aspects of the RNA-centric perspective in neurobiology:

• 
  Non-Coding RNAs


• 
  miRNAs


• 
  lncRNAs


• 
  circRNAs


• 
  RNA Editing


• 
  RNA Transport and Local Translation


• 
  Neurodevelopment and Plasticity


• 
  Neurological Disorders


• 
  Technological Advances


• 
  Therapeutic Potential

The discovery of a new and rare form of dementia represents an important advancement in the field of neurology and can have significant implications for diagnosis, treatment, and understanding the underlying mechanisms of the condition.

Here's how the discovery process might unfold:

• Clinical Observations
• Diagnostic Challenges
• Collaboration
• Data Collection
• Pathological Studies
• Publication and Communication
• Naming and Classification
• Impact and Implications
• Ongoing Research

Neurodegeneration refers to the progressive degeneration or deterioration of neurons (nerve cells) in the nervous system.

Here are some key points about neurodegeneration and degenerative diseases:

• Common Neurodegenerative Diseases
• Pathological Mechanisms
• Genetic Factors
• Diagnosis and Monitoring
• Current Treatments
• Research and Future Directions

Neurological pain syndromes are a group of conditions characterized by persistent and often severe pain that arises from dysfunction or damage to the nervous system.

Here are some examples of neurological pain syndromes:

• Trigeminal Neuralgia
• Postherpetic Neuralgia
• Complex Regional Pain Syndrome (CRPS)
• Neuropathic Pain
• Phantom Limb Pain
• Central Pain Syndrome
• Occipital Neuralgia
• Cluster Headaches
• Fibromyalgia

Neurogenetics is a branch of genetics that focuses on the role of genetics in the development and functioning of the nervous system. Neurological disorders are conditions that affect the nervous system, including the brain, spinal cord, and peripheral nerves.

Here are some key aspects of the relationship between neurogenetics and neurological disorders:

• 
  Genetic Variants and Mutations


• 
  Monogenic Neurological Disorders


• 
  Complex Genetic Factors


• 
  Hereditary Disorders


• 
  Genetic Testing and Diagnosis


• 
  Predictive Genetic Testing


• 
  Gene Therapy and Targeted Treatments


• 
  Genetic Counseling


• 
  Ethical Considerations

Stem cells hold significant potential for neuron regeneration and repair in the nervous system. Neuron regeneration refers to the process of generating new neurons (nerve cells) to replace damaged or lost neurons.

Here are some key concepts related to stem cells and neuron regeneration:

Types of Stem Cells

• Embryonic Stem Cells (ESCs)
• Induced Pluripotent Stem Cells (iPSCs)
• Adult Stem Cells (Somatic Stem Cells)

Neurogenesis in the Brain
Stem Cell Transplantation
Neurological Disorders and Injuries
Challenges and Considerations
Research and Clinical Trials

Multiple sclerosis is an autoimmune disorder that primarily affects the central nervous system (brain and spinal cord)

Key points about multiple sclerosis include:

• Symptoms
• Relapses and Remissions
• Diagnosis
• Causes
• Treatment

Neurofibromatosis (NF) refers to a group of genetic disorders that affect the growth and development of nerve tissues. There are two main types: Neurofibromatosis Type 1 (NF1) and Neurofibromatosis Type 2 (NF2).

Key points about neurofibromatosis include:

• Symptoms
• Genetic Basis
• Diagnosis
• Treatment
• Prognosis

Cognitive neuroscience is the field of study that investigates the neural basis of cognitive processes, such as perception, attention, memory, language, decision-making, and problem-solving. Dementia, on the other hand, is a broad term used to describe a decline in cognitive function severe enough to interfere with a person's daily life and activities.

Here's how cognitive neuroscience and dementia are related:

• Understanding Cognitive Processes
• Mapping Brain Changes in Dementia
• Early Detection and Diagnosis
• Exploring Neural Correlates of Symptoms
• Differentiating Types of Dementia
• Development of Interventions
• Evaluating Treatment Efficacy
• Enhancing Caregiver Understanding
• Promoting Public Awareness

Protein interactions are fundamental processes in neuroscience that underlie the complex functions of the nervous system. Neurons communicate and perform their functions through intricate networks of proteins that interact with each other to regulate signaling, gene expression, structural integrity, and other critical processes.

Here are some key aspects of protein interactions in neuroscience:

• Synaptic Transmission
• Receptor-Ligand Interactions
• Signal Transduction Pathways
• Neurotrophic Factors
• Synaptic Plasticity
• Cytoskeletal Proteins
• Intracellular Signaling
• Protein-Protein Interactions
• Cell Adhesion Proteins
• Molecular Chaperones
• Drug Targets

Neuroinformatics is an interdisciplinary field that involves the integration of information technology, computational methods, and neuroscience to facilitate the collection, organization, analysis, and sharing of large and complex neuroscience data.

Key aspects of neuroinformatics include:

• Data Management and Sharing
• Data Analysis
• Modeling and Simulation
• Neuroimaging Informatics
• Connectomics
• Genomic and Transcriptomic Data
• Data Standards and Ontologies
• Machine Learning and AI

Neurotechnology involves the development of tools, techniques, and devices that interface with the nervous system to study, manipulate, or restore its function. Neurotechnology has a wide range of applications, from basic research to clinical interventions.

Key areas of neurotechnology include:

• Neuroimaging Technologies
• Electrophysiology
• Neural Recording and Stimulation
• Brain-Machine Interfaces (BMIs)
• Neuromodulation
• Neuroprosthetics
• Neurofeedback
• Optogenetics

Molecular and cellular neuroscience is a branch of neuroscience that focuses on understanding the fundamental biological processes that govern the structure and function of the nervous system at the molecular and cellular levels.

Key areas of study within molecular and cellular neuroscience include:

• Neuronal Signaling and Communication
• Neurotransmitters and Neurotransmission
• Neuroplasticity
• Ion Channels and Electrical Excitability
• Intracellular Signaling Pathways
• Neurogenesis and Cell Fate
• Gene Expression and Regulation

Artificial Intelligence (AI) has made significant contributions to the field of neuroimaging, revolutionizing the way medical professionals analyze and interpret complex brain images. Neuroimaging techniques, such as MRI (Magnetic Resonance Imaging), CT (Computed Tomography), PET (Positron Emission Tomography), and fMRI (functional Magnetic Resonance Imaging), generate vast amounts of data that can be challenging to process and interpret manually.

Here are some ways AI is impacting neuroimaging:

• Image Segmentation and Analysis
• Disease Detection and Diagnosis
• Radiomics and Feature Extraction
• Predictive Modeling
• Functional Connectivity Analysis
• Automated Quality Control
• Neurodegenerative Disease Tracking
• Drug Development and Clinical Trials
• Data Fusion and Integration

Neuro-oncology is a medical specialty that focuses on the diagnosis, treatment, and management of brain and spinal cord tumors.

Key aspects of neuro-oncology include:

• Tumor Diagnosis
• Tumor Classification
• Treatment Planning
• Multidisciplinary Care
• Palliative Care
• Clinical Trials

Cerebrovascular diseases involve disorders of blood vessels in the brain, including arteries and veins.

Key aspects of cerebrovascular diseases include:

• Stroke Diagnosis and Treatment
• Vascular Malformations
• Aneurysms
• Vascular Imaging
• Interventional Procedures
• Preventive Strategies

Neuro-ophthalmology is a subspecialty within both neurology and ophthalmology that focuses on the complex interplay between the nervous system and the visual system. It involves the evaluation, diagnosis, and management of visual and neurological disorders that affect the eye, optic nerve, and the parts of the brain responsible for vision.

Key areas of focus within neuro-ophthalmology include:

• Optic Nerve Disorders
• Visual Field Defects
• Pupillary Abnormalities
• Ocular Motility Disorders
• Cranial Nerve Abnormalities
• Headache and Migraine
• Neurological Examinations
• Diagnostic Testing

Clinical neurophysiology is a medical specialty that focuses on the study and assessment of the electrical activity of the nervous system. It involves the use of various techniques to measure and analyze the electrical signals generated by the brain, spinal cord, nerves, and muscles. These techniques provide valuable insights into the functioning and health of the nervous system, helping diagnose and manage a wide range of neurological and neuromuscular disorders.

Key components of clinical neurophysiology include:

• Electroencephalography (EEG)
• Electromyography (EMG)
• Nerve Conduction Studies (NCS)
• Evoked Potentials (EP)
• Polysomnography (PSG)